For doctors

Information for healthcare practitioners

Interested in partnering with us?

Are you a healthcare practitioner interested in supporting families with deeper gut health insights? We collaborate with clinics, midwives, dietitians, and pediatric professionals who want to offer Alba Health testing and guidance to their patients.

Who are we?

What we do now

We leverage established microbiome science, digital technologies and AI. We build digital products that help families lead a healthier life focused on wellbeing, based on established science.

Our mid-term objectives

To better diagnose, reduce symptoms and ultimately prevent health risks (upon regulatory approval). To gather millions of real world data-points to advance research.

Our long-term vision

A world where every family has personalised support to lead a healthy life and prevent chronic conditions. A real-world dataset to advance our understanding of chronic diseases with university partners.

SCIENTIFIC ADVISORY BOARD

Backed by a team of experts

Prof. Willem De vos

PhD

About

Dr. Jakob Stokholm

MD, PhD

About

Prof. Nele Brusselaers

MD, PhD

About

Dr. Erica Bonns

MD

About

Prof. Luisa W. Hugerth

PhD

About

Dr. Majdi Osman

MD

About

Prof. Robert Brummer

MD

About

Prof. Yvan Vandeplas

MD

About

Dr. Colette Reynolds

PhD

About

Prof. Willem De vos

PhD

About

Prof. Robert Brummer

MD

About

Prof. Luisa W. Hugerth

PhD

About

Prof. Nele Brusselaers

MD, PhD

About

Dr. Colette Reynolds

PhD

About

Dr. Erica Bonns

MD

About

Dr. Jakob Stokholm

MD, PhD

About

Prof. Yvan Vandeplas

MD

About

Dr. Majdi Osman

MD

About

What do we know about the gut microbiome?

Although there is still a lot we don’t know about our microbiome, gut microbiome research has gained a lot of attention over the last years [1]. Scientific publications on the human gut microbiome have increased over ten-fold over the past decade alone [2], strengthening the correlations between the gut microbiome and health during early life and providing insight in its mechanisms [3]. Moreover, there is increasing support for the notion that early life microbial colonisation affects life-long health.

Gut microbiome and common childhood symptoms

Gut microbiome in early life and chronic diseases later in life

Gut microbiome and immune system development

The main disruptors of infant gut microbiome development

Gut microbiome and interventions

Still have questions?

How do we analyse the gut microbiome at Alba?

Alba Health asks parents to provide a stool sample from the diaper of their child, meaning that this procedure is non-invasive and does not require parents to make any changes in their daily routine. Alba Health uses deep shotgun metagenomics sequencing technology to analyse extracted DNA from the infant stool samples. This method provides comprehensive microbiome profiling, including bacteria, fungi, viruses, protozoa and bacteriophages and enables characterisation of the microbiome composition.

This is the most advanced technology used in microbiome research today with the highest output, offering both insights into composition and functionality.

Shotgun Metagenomics

16S RNA

amplicon

RNA

sequencing

qPCR

General composition

General composition

Species level resolution

Species level resolution

Functional analysis

Functional analysis

Antibiotic resistance markers

Antibiotic resistance markers

Prediction of metabolic pathways

Prediction of metabolic pathways

What is the PREVENT study about?

Alba Health has launched its first research study mapping the connection between the gut microbiome and lifestyle, wellbeing and health during the first year of life.

Research aim and hyphothesis

  • The main aim of this study is to assess the association between the infant microbiome during the first year of life and health over a 6 months period using extensive metadata collection.

  • Our secondary aim is to develop machine-learning models to predict core microbiome markers based on stool characteristics.

  • Our third and final aim is to evaluate if a recording of infant crying can be a tool to decrease the burden of first-time parents on understanding their infant's needs.

If our hypothesis is correct, key age points are significant predictors for microbiome development, which correlates to introducing different foods to the infant's diet. The study and definition of what is to be considered a healthy microbiome constitution for these windows of time may allow for dietary interventions, good immune development of the child, and possibly prevention of complications.

Study design

The PREVENT study is an observational study, meaning that we do not ask participants to change their daily routine and they will be able to participate from their own home and no doctor’s visits are needed. All research will be carried out in Sweden.

Legal guidelines

This study has been approved by the Swedish Ethics Review Authority (registration nr. 2023-05299-01)

All data is handled in accordance with GDPR, Swedish law and informed consent.

All participants are asked to provide their informed consent before they begin any study activities.

References